Increased sporulation underpins adaptation of Clostridium difficile strain 630 to a biologically–relevant faecal environment, with implications for pathogenicity

Clostridium difficile virulence is driven primarily by the processes of toxinogenesis and sporulation, however many in vitro experimental systems for studying C. difficile physiology have arguably limited relevance to the human colonic environment. We therefore created a more physiologically–relevan...

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Detalles Bibliográficos
Autores principales: Ternan, Nigel George, Moore, Nicola Diana, Smyth, Deborah, McDougall, Gordon James, Allwood, James William, Verrall, Susan, Gill, Christopher Ian Richard, Dooley, James Stephen Gerard, McMullan, Geoff
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232153/
https://www.ncbi.nlm.nih.gov/pubmed/30420658
http://dx.doi.org/10.1038/s41598-018-35050-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232153/
https://www.ncbi.nlm.nih.gov/pubmed/30420658
http://dx.doi.org/10.1038/s41598-018-35050-x

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