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Increased sporulation underpins adaptation of Clostridium difficile strain 630 to a biologically–relevant faecal environment, with implications for pathogenicity
Clostridium difficile virulence is driven primarily by the processes of toxinogenesis and sporulation, however many in vitro experimental systems for studying C. difficile physiology have arguably limited relevance to the human colonic environment. We therefore created a more physiologically–relevan...
Autores principales: | Ternan, Nigel George, Moore, Nicola Diana, Smyth, Deborah, McDougall, Gordon James, Allwood, James William, Verrall, Susan, Gill, Christopher Ian Richard, Dooley, James Stephen Gerard, McMullan, Geoff |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232153/ https://www.ncbi.nlm.nih.gov/pubmed/30420658 http://dx.doi.org/10.1038/s41598-018-35050-x |
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