Human adipose glycerol flux is regulated by a pH gate in AQP10

Obesity is a major threat to global health and metabolically associated with glycerol homeostasis. Here we demonstrate that in human adipocytes, the decreased pH observed during lipolysis (fat burning) correlates with increased glycerol release and stimulation of aquaglyceroporin AQP10. The crystal...

Descripción completa

Detalles Bibliográficos
Autores principales: Gotfryd, Kamil, Mósca, Andreia Filipa, Missel, Julie Winkel, Truelsen, Sigurd Friis, Wang, Kaituo, Spulber, Mariana, Krabbe, Simon, Hélix-Nielsen, Claus, Laforenza, Umberto, Soveral, Graça, Pedersen, Per Amstrup, Gourdon, Pontus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232157/
https://www.ncbi.nlm.nih.gov/pubmed/30420639
http://dx.doi.org/10.1038/s41467-018-07176-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232157/
https://www.ncbi.nlm.nih.gov/pubmed/30420639
http://dx.doi.org/10.1038/s41467-018-07176-z

Ejemplares similares