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Downregulation of VEGFR3 signaling alters cardiac lymphatic vessel organization and leads to a higher mortality after acute myocardial infarction

Heart has a wide lymphatic network but the importance of cardiac lymphatic system in heart diseases has remained unclear. Vascular Endothelial Growth Factor Receptor 3 (VEGFR3) is a key molecule in the development and maintenance of cardiac lymphatic vessels. Here we characterized the role of VEGFR3...

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Detalles Bibliográficos
Autores principales: Vuorio, Taina, Ylä-Herttuala, Elias, Laakkonen, Johanna P., Laidinen, Svetlana, Liimatainen, Timo, Ylä-Herttuala, Seppo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232169/
https://www.ncbi.nlm.nih.gov/pubmed/30420641
http://dx.doi.org/10.1038/s41598-018-34770-4