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Similar Gastro-Intestinal Exposure to Florfenicol After Oral or Intramuscular Administration in Pigs, Leading to Resistance Selection in Commensal Escherichia coli

Florfenicol, which is licensed for veterinary use only, proves to be a potent antimicrobial for treatment of respiratory disease. However, the subsequent exposure of the gut microbiota to florfenicol is not well described. Hence, the effect of various administration protocols on both plasma and gast...

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Detalles Bibliográficos
Autores principales: De Smet, Joren, Boyen, Filip, Croubels, Siska, Rasschaert, Geertrui, Haesebrouck, Freddy, De Backer, Patrick, Devreese, Mathias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232271/
https://www.ncbi.nlm.nih.gov/pubmed/30459619
http://dx.doi.org/10.3389/fphar.2018.01265