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The Antihistamine Drugs Carbinoxamine Maleate and Chlorpheniramine Maleate Exhibit Potent Antiviral Activity Against a Broad Spectrum of Influenza Viruses

Influenza A viruses (IAV) comprise some of the most common infectious pathogens in humans, and they cause significant mortality and morbidity in immunocompromised people as well as children and the elderly. After screening an FDA-approved drug library containing 1280 compounds by cytopathic effect (...

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Detalles Bibliográficos
Autores principales: Xu, Wei, Xia, Shuai, Pu, Jing, Wang, Qian, Li, Peiyu, Lu, Lu, Jiang, Shibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232386/
https://www.ncbi.nlm.nih.gov/pubmed/30459739
http://dx.doi.org/10.3389/fmicb.2018.02643