Enhanced mitochondrial pyruvate transport elicits a robust ROS production to sensitize the antitumor efficacy of interferon-γ in colon cancer

Metabolic reprogramming is a feature of cancer cells and crucial for tumor growth and metastasis. Interferon-γ (IFNγ) is a cytokine that plays a pivotal role in host antitumor immunity. However, little is known about the roles of metabolic reprogramming in immune responses. Here, we show that colon...

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Detalles Bibliográficos
Autores principales: Tai, YunYan, Cao, Fengjun, Li, Mingxing, Li, Pindong, Xu, Tao, Wang, Xuanbin, Yu, Yuandong, Gu, Bing, Yu, Xiongjie, Cai, Xiaojun, Ao, Feng, Ge, Peng, Xiang, Longchao, Yang, Bingbing, Jiang, Yingpin, Li, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232645/
https://www.ncbi.nlm.nih.gov/pubmed/30439686
http://dx.doi.org/10.1016/j.redox.2018.10.024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232645/
https://www.ncbi.nlm.nih.gov/pubmed/30439686
http://dx.doi.org/10.1016/j.redox.2018.10.024

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