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Hyperglycemia aggravates microenvironment hypoxia and promotes the metastatic ability of pancreatic cancer

BACKGROUND: Diabetes mellitus and pancreatic cancer are intimately related. Our previous studies showed that high levels of blood glucose promote epithelial-mesenchymal transition of pancreatic cancer. In this study, we evaluated the relationship between hyperglycemia and hypoxic tumor microenvironm...

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Detalles Bibliográficos
Autores principales: Li, Wei, Liu, Han, Qian, Weikun, Cheng, Liang, Yan, Bin, Han, Liang, Xu, Qinhong, Ma, Qingyong, Ma, Jiguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232646/
https://www.ncbi.nlm.nih.gov/pubmed/30455857
http://dx.doi.org/10.1016/j.csbj.2018.10.006