GLP-1 Improves Adipocyte Insulin Sensitivity Following Induction of Endoplasmic Reticulum Stress

Glucagon-like peptide 1 (GLP-1) improves insulin resistance of adipose tissue in obese humans. However, the mechanism of this effect is unclear. Perturbation of endoplasmic reticulum (ER) homeostasis impairs insulin signaling. We hypothesized that GLP-1 could directly improve insulin signaling in ER...

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Detalles Bibliográficos
Autores principales: Jiang, Yaojing, Wang, Zhihong, Ma, Bo, Fan, Linling, Yi, Na, Lu, Bin, Wang, Qinghua, Liu, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232689/
https://www.ncbi.nlm.nih.gov/pubmed/30459598
http://dx.doi.org/10.3389/fphar.2018.01168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232689/
https://www.ncbi.nlm.nih.gov/pubmed/30459598
http://dx.doi.org/10.3389/fphar.2018.01168

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