Icariin Ameliorates Palmitate-Induced Insulin Resistance Through Reducing Thioredoxin-Interacting Protein (TXNIP) and Suppressing ER Stress in C2C12 Myotubes

Both thioredoxin-interacting protein (TXNIP) and endoplasmic reticulum (ER) stress are implicated in skeletal muscle insulin resistance. Icariin has been found to mimic insulin action in normal skeletal muscle C2C12 cells and display anti-diabetic properties in diet-induced obese mice. However, the...

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Detalles Bibliográficos
Autores principales: Li, Mingxin, Zhang, Yemin, Cao, Yingkang, Zhang, Deling, Liu, Le, Guo, Yanghongyun, Wang, Changhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232724/
https://www.ncbi.nlm.nih.gov/pubmed/30459603
http://dx.doi.org/10.3389/fphar.2018.01180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232724/
https://www.ncbi.nlm.nih.gov/pubmed/30459603
http://dx.doi.org/10.3389/fphar.2018.01180

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