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Nitroglycerin and Iloprost Improve Mitochondrial Function in Colon Homogenate Without Altering the Barrier Integrity of Caco-2 Monolayers

Locally applied nitroglycerin [nitric oxide (NO) donor] and iloprost (analog of prostacyclin PGI(2)) improve regional gastric oxygenation and nitroglycerin preserves gastric mucosal barrier integrity. This suggests direct effects of these substances on oxygenation and barrier function. The aim of th...

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Detalles Bibliográficos
Autores principales: Herminghaus, Anna, Eberhardt, Rebecca, Truse, Richard, Schulz, Jan, Bauer, Inge, Picker, Olaf, Vollmer, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232762/
https://www.ncbi.nlm.nih.gov/pubmed/30460235
http://dx.doi.org/10.3389/fmed.2018.00291