Extended Cleavage Specificity of Human Neutrophil Elastase, Human Proteinase 3, and Their Distant Ortholog Clawed Frog PR3—Three Elastases With Similar Primary but Different Extended Specificities and Stability

Serine proteases are major granule constituents of several of the human hematopoietic cell lineages. Four proteolytically active such proteases have been identified in human neutrophils: cathepsin G (hCG), N-elastase (hNE), proteinase 3 (hPR-3), and neutrophil serine protease 4 (hNSP-4). Here we pre...

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Detalles Bibliográficos
Autores principales: Fu, Zhirong, Thorpe, Michael, Akula, Srinivas, Chahal, Gurdeep, Hellman, Lars T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232827/
https://www.ncbi.nlm.nih.gov/pubmed/30459762
http://dx.doi.org/10.3389/fimmu.2018.02387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232827/
https://www.ncbi.nlm.nih.gov/pubmed/30459762
http://dx.doi.org/10.3389/fimmu.2018.02387

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