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Gears-In-Motion: The Interplay of WW and PPIase Domains in Pin1

Pin1 belongs to the family of the peptidyl-prolyl cis-trans isomerase (PPIase), which is a class of enzymes that catalyze the cis/trans isomerization of the Proline residue. Pin1 is unique and only catalyzes the phosphorylated Serine/Threonine-Proline (S/T-P) motifs of a subset of proteins. Since th...

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Detalles Bibliográficos
Autores principales: Lee, Yew Mun, Liou, Yih-Cherng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232885/
https://www.ncbi.nlm.nih.gov/pubmed/30460195
http://dx.doi.org/10.3389/fonc.2018.00469