Cargando…

Astilbin Inhibits High Glucose-Induced Inflammation and Extracellular Matrix Accumulation by Suppressing the TLR4/MyD88/NF-κB Pathway in Rat Glomerular Mesangial Cells

Diabetic nephropathy (DN) is characterized by inflammatory responses and extracellular matrix (ECM) accumulation. Astilbin is an active natural compound and possesses anti-inflammatory activity. The aim of this study was to evaluate the anti-inflammatory effect of astilbin on high glucose (HG)-induc...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Fang, Zhu, Xiaoguang, Sun, Zhiqiang, Ma, Yali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232904/
https://www.ncbi.nlm.nih.gov/pubmed/30459606
http://dx.doi.org/10.3389/fphar.2018.01187