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Deciphering the Role of Regulatory CD4 T Cells in Oral and Oropharyngeal Cancer: A Systematic Review

Background: Recruiting regulatory CD4 T cells (Tregs) into the tumor microenvironment is an important tumor escape mechanism. Diminishing these suppressive cells is therefore one of the targets of cancer immunotherapy. Selective depletion of Tregs has proven successful in enhancing anti-tumor immuni...

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Detalles Bibliográficos
Autores principales: O'Higgins, Caoimhín, Ward, Frank J., Abu Eid, Rasha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232931/
https://www.ncbi.nlm.nih.gov/pubmed/30460193
http://dx.doi.org/10.3389/fonc.2018.00442