Correlation of CRM1-NES affinity with nuclear export activity

CRM1 (Exportin1/XPO1) exports hundreds of broadly functioning protein cargoes out of the cell nucleus by binding to their classical nuclear export signals (NESs). The 8- to 15-amino-acid-long NESs contain four to five hydrophobic residues and are highly diverse in both sequence and CRM1-bound struct...

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Detalles Bibliográficos
Autores principales: Fu, Szu-Chin, Fung, Ho Yee Joyce, Cağatay, Tolga, Baumhardt, Jordan, Chook, Yuh Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2018
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232958/
https://www.ncbi.nlm.nih.gov/pubmed/29927350
http://dx.doi.org/10.1091/mbc.E18-02-0096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232958/
https://www.ncbi.nlm.nih.gov/pubmed/29927350
http://dx.doi.org/10.1091/mbc.E18-02-0096

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