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Protein phosphatase 2A is crucial for sarcomere organization in Caenorhabditis elegans striated muscle

Protein phosphatase 2A (PP2A) is a heterotrimer composed of single catalytic and scaffolding subunits and one of several possible regulatory subunits. We identified PPTR-2, a regulatory subunit of PP2A, as a binding partner for the giant muscle protein UNC-89 (obscurin) in Caenorhabditis elegans. PP...

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Detalles Bibliográficos
Autores principales: Qadota, Hiroshi, Matsunaga, Yohei, Bagchi, Pritha, Lange, Karen I., Carrier, Karma J., Pols, William Vander, Swartzbaugh, Emily, Wilson, Kristy J., Srayko, Martin, Pallas, David C., Benian, Guy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232960/
https://www.ncbi.nlm.nih.gov/pubmed/29949401
http://dx.doi.org/10.1091/mbc.E18-03-0192