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Coupling of microtubule motors with AP-3 generated organelles in axons by NEEP21 family member calcyon

Transport of late endosomes and lysosome-related organelles (LE/LROs) in axons is essential for supplying synaptic cargoes and for removing damaged macromolecules. Defects in this system are implicated in a range of human neurodegenerative and neurodevelopmental disorders. The findings reported here...

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Detalles Bibliográficos
Autores principales: Shi, Liang, Hines, Timothy, Bergson, Clare, Smith, Deanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232961/
https://www.ncbi.nlm.nih.gov/pubmed/29949458
http://dx.doi.org/10.1091/mbc.E18-01-0007