Constricted migration increases DNA damage and independently represses cell cycle

Cell migration through dense tissues or small capillaries can elongate the nucleus and even damage it, and any impact on cell cycle has the potential to affect various processes including carcinogenesis. Here, nuclear rupture and DNA damage increase with constricted migration in different phases of...

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Detalles Bibliográficos
Autores principales: Pfeifer, Charlotte R., Xia, Yuntao, Zhu, Kuangzheng, Liu, Dazhen, Irianto, Jerome, García, Victor M. Morales, Millán, Leeza M. Santiago, Niese, Brandon, Harding, Shane, Deviri, Dan, Greenberg, Roger A., Discher, Dennis E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232975/
https://www.ncbi.nlm.nih.gov/pubmed/29742017
http://dx.doi.org/10.1091/mbc.E18-02-0079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232975/
https://www.ncbi.nlm.nih.gov/pubmed/29742017
http://dx.doi.org/10.1091/mbc.E18-02-0079

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