Cargando…

Remodeling neuronal ER–PM junctions is a conserved nonconducting function of Kv2 plasma membrane ion channels

The endoplasmic reticulum (ER) and plasma membrane (PM) form junctions crucial to ion and lipid signaling and homeostasis. The Kv2.1 ion channel is localized at ER–PM junctions in brain neurons and is unique among PM proteins in its ability to remodel these specialized membrane contact sites. Here,...

Descripción completa

Detalles Bibliográficos
Autores principales: Kirmiz, Michael, Palacio, Stephanie, Thapa, Parashar, King, Anna N., Sack, Jon T., Trimmer, James S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233057/
https://www.ncbi.nlm.nih.gov/pubmed/30091655
http://dx.doi.org/10.1091/mbc.E18-05-0337