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Effects of human sex chromosome dosage on spatial chromosome organization

Sex chromosome aneuploidies (SCAs) are common genetic syndromes characterized by the presence of an aberrant number of X and Y chromosomes due to meiotic defects. These conditions impact the structure and function of diverse tissues, but the proximal effects of SCAs on genome organization are unknow...

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Detalles Bibliográficos
Autores principales: Jowhar, Ziad, Shachar, Sigal, Gudla, Prabhakar R., Wangsa, Darawalee, Torres, Erin, Russ, Jill L., Pegoraro, Gianluca, Ried, Thomas, Raznahan, Armin, Misteli, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233059/
https://www.ncbi.nlm.nih.gov/pubmed/30091656
http://dx.doi.org/10.1091/mbc.E18-06-0359