Cargando…
Effects of human sex chromosome dosage on spatial chromosome organization
Sex chromosome aneuploidies (SCAs) are common genetic syndromes characterized by the presence of an aberrant number of X and Y chromosomes due to meiotic defects. These conditions impact the structure and function of diverse tissues, but the proximal effects of SCAs on genome organization are unknow...
Autores principales: | Jowhar, Ziad, Shachar, Sigal, Gudla, Prabhakar R., Wangsa, Darawalee, Torres, Erin, Russ, Jill L., Pegoraro, Gianluca, Ried, Thomas, Raznahan, Armin, Misteli, Tom |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233059/ https://www.ncbi.nlm.nih.gov/pubmed/30091656 http://dx.doi.org/10.1091/mbc.E18-06-0359 |
Ejemplares similares
-
Quantitative detection of rare interphase chromosome breaks and translocations by high-throughput imaging
por: Burman, Bharat, et al.
Publicado: (2015) -
Single Chromosome Aneuploidy Induces Genome-Wide Perturbation of Nuclear Organization and Gene Expression
por: Braun, Rüdiger, et al.
Publicado: (2019) -
Chromosome mis-segregation and cytokinesis failure in trisomic human cells
por: Nicholson, Joshua M, et al.
Publicado: (2015) -
Concurrent V(D)J recombination and DNA end instability increase interchromosomal trans-rearrangements in ATM-deficient thymocytes
por: Bowen, Steven, et al.
Publicado: (2013) -
TP53 loss initiates chromosomal instability in fallopian tube epithelial cells
por: Bronder, Daniel, et al.
Publicado: (2021)