Endoplasmic reticulum–associated degradation and disposal of misfolded GPI-anchored proteins in Trypanosoma brucei

Misfolded secretory proteins are retained by endoplasmic reticulum quality control (ERQC) and degraded in the proteasome by ER-associated degradation (ERAD). However, in yeast and mammals, misfolded glycosylphosphatidylinositol (GPI)-anchored proteins are preferentially degraded in the vacuole/lysos...

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Detalles Bibliográficos
Autores principales: Tiengwe, Calvin, Koeller, Carolina M., Bangs, James D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233060/
https://www.ncbi.nlm.nih.gov/pubmed/30091673
http://dx.doi.org/10.1091/mbc.E18-06-0380

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233060/
https://www.ncbi.nlm.nih.gov/pubmed/30091673
http://dx.doi.org/10.1091/mbc.E18-06-0380

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