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Cancer cells’ ability to mechanically adjust to extracellular matrix stiffness correlates with their invasive potential

Increased tissue stiffness is a classic characteristic of solid tumors. One of the major contributing factors is increased density of collagen fibers in the extracellular matrix (ECM). Here, we investigate how cancer cells biomechanically interact with and respond to the stiffness of the ECM. Probin...

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Detalles Bibliográficos
Autores principales: Wullkopf, Lena, West, Ann-Katrine V., Leijnse, Natascha, Cox, Thomas R., Madsen, Chris D., Oddershede, Lene B., Erler, Janine T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233061/
https://www.ncbi.nlm.nih.gov/pubmed/30091653
http://dx.doi.org/10.1091/mbc.E18-05-0319