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Noggin rescues age-related stem cell loss in the brain of senescent mice with neurodegenerative pathology

Increasing age is the greatest known risk factor for the sporadic late-onset forms of neurodegenerative disorders such as Alzheimer’s disease (AD). One of the brain regions most severely affected in AD is the hippocampus, a privileged structure that contains adult neural stem cells (NSCs) with neuro...

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Detalles Bibliográficos
Autores principales: Díaz-Moreno, María, Armenteros, Tomás, Gradari, Simona, Hortigüela, Rafael, García-Corzo, Laura, Fontán-Lozano, Ángela, Trejo, José Luis, Mira, Helena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233090/
https://www.ncbi.nlm.nih.gov/pubmed/30352848
http://dx.doi.org/10.1073/pnas.1813205115