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Noggin rescues age-related stem cell loss in the brain of senescent mice with neurodegenerative pathology
Increasing age is the greatest known risk factor for the sporadic late-onset forms of neurodegenerative disorders such as Alzheimer’s disease (AD). One of the brain regions most severely affected in AD is the hippocampus, a privileged structure that contains adult neural stem cells (NSCs) with neuro...
Autores principales: | Díaz-Moreno, María, Armenteros, Tomás, Gradari, Simona, Hortigüela, Rafael, García-Corzo, Laura, Fontán-Lozano, Ángela, Trejo, José Luis, Mira, Helena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233090/ https://www.ncbi.nlm.nih.gov/pubmed/30352848 http://dx.doi.org/10.1073/pnas.1813205115 |
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