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The mechanism of resistance to favipiravir in influenza

Favipiravir is a broad-spectrum antiviral that has shown promise in treatment of influenza virus infections. While emergence of resistance has been observed for many antiinfluenza drugs, to date, clinical trials and laboratory studies of favipiravir have not yielded resistant viruses. Here we show e...

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Detalles Bibliográficos
Autores principales: Goldhill, Daniel H., te Velthuis, Aartjan J. W., Fletcher, Robert A., Langat, Pinky, Zambon, Maria, Lackenby, Angie, Barclay, Wendy S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233120/
https://www.ncbi.nlm.nih.gov/pubmed/30352857
http://dx.doi.org/10.1073/pnas.1811345115