Cargando…
The mechanism of resistance to favipiravir in influenza
Favipiravir is a broad-spectrum antiviral that has shown promise in treatment of influenza virus infections. While emergence of resistance has been observed for many antiinfluenza drugs, to date, clinical trials and laboratory studies of favipiravir have not yielded resistant viruses. Here we show e...
Autores principales: | Goldhill, Daniel H., te Velthuis, Aartjan J. W., Fletcher, Robert A., Langat, Pinky, Zambon, Maria, Lackenby, Angie, Barclay, Wendy S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233120/ https://www.ncbi.nlm.nih.gov/pubmed/30352857 http://dx.doi.org/10.1073/pnas.1811345115 |
Ejemplares similares
-
Determining the Mutation Bias of Favipiravir in Influenza Virus Using Next-Generation Sequencing
por: Goldhill, Daniel H., et al.
Publicado: (2019) -
Favipiravir-resistant influenza A virus shows potential for transmission
por: Goldhill, Daniel H., et al.
Publicado: (2021) -
Pandemic H1N1 2009 influenza virus with the H275Y oseltamivir resistance neuraminidase mutation shows a small compromise in enzyme activity and viral fitness
por: Brookes, Daniel W., et al.
Publicado: (2011) -
A Mechanism for Priming and Realignment during Influenza A Virus Replication
por: Oymans, Judith, et al.
Publicado: (2018) -
Single-molecule FRET reveals the pre-initiation and initiation conformations of influenza virus promoter RNA
por: Robb, Nicole C., et al.
Publicado: (2016)