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MicroRNA-182 Alleviates Neuropathic Pain by Regulating Nav1.7 Following Spared Nerve Injury in Rats

The sodium channel 1.7 (Nav1.7), which is encoded by SCN9A gene, is involved in neuropathic pain. As crucial regulators of gene expression, many miRNAs have already gained importance in neuropathic pain, including miR-182, which is predicted to regulate the SCN9A gene. Nav1.7 expression in L4-L6 dor...

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Detalles Bibliográficos
Autores principales: Cai, Weihua, Zhao, Qingzan, Shao, Jinping, Zhang, Jingjing, Li, Lei, Ren, Xiuhua, Su, Songxue, Bai, Qian, Li, Ming, Chen, Xuemei, Wang, Jian, Cao, Jing, Zang, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233159/
https://www.ncbi.nlm.nih.gov/pubmed/30425258
http://dx.doi.org/10.1038/s41598-018-34755-3