ME1 promotes basal-like breast cancer progression and associates with poor prognosis

Basal-like breast cancer (BLBC) is associated with a poor clinical outcome due to the few treatment options and absence of effective targeted agents. Here, we show that malic enzyme 1 (ME1) is dramatically upregulated in BLBC due to ME1 copy number amplification. ME1 expression increases glucose upt...

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Detalles Bibliográficos
Autores principales: Liao, Ruocen, Ren, Guoping, Liu, Huixin, Chen, Xingyu, Cao, Qianhua, Wu, Xuebiao, Li, Jun, Dong, Chenfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233160/
https://www.ncbi.nlm.nih.gov/pubmed/30425310
http://dx.doi.org/10.1038/s41598-018-35106-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233160/
https://www.ncbi.nlm.nih.gov/pubmed/30425310
http://dx.doi.org/10.1038/s41598-018-35106-y

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