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The anti-tumor diterpene oridonin is a direct inhibitor of Nucleolin in cancer cells

The bioactive plant diterpene oridonin displays important pharmacological activities and is widely used in traditional Chinese medicine; however, its molecular mechanism of action is still incompletely described. In vitro and in vivo data have demonstrated anti-tumor activity of oridonin and its abi...

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Detalles Bibliográficos
Autores principales: Vasaturo, Michele, Cotugno, Roberta, Fiengo, Lorenzo, Vinegoni, Claudio, Dal Piaz, Fabrizio, De Tommasi, Nunziatina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233161/
https://www.ncbi.nlm.nih.gov/pubmed/30425290
http://dx.doi.org/10.1038/s41598-018-35088-x