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The anti-tumor diterpene oridonin is a direct inhibitor of Nucleolin in cancer cells
The bioactive plant diterpene oridonin displays important pharmacological activities and is widely used in traditional Chinese medicine; however, its molecular mechanism of action is still incompletely described. In vitro and in vivo data have demonstrated anti-tumor activity of oridonin and its abi...
Autores principales: | Vasaturo, Michele, Cotugno, Roberta, Fiengo, Lorenzo, Vinegoni, Claudio, Dal Piaz, Fabrizio, De Tommasi, Nunziatina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233161/ https://www.ncbi.nlm.nih.gov/pubmed/30425290 http://dx.doi.org/10.1038/s41598-018-35088-x |
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