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Hepatokine α1-Microglobulin Signaling Exacerbates Inflammation and Disturbs Fibrotic Repair in Mouse Myocardial Infarction

Acute cardiac rupture and adverse left ventricular (LV) remodeling causing heart failure are serious complications of acute myocardial infarction (MI). While cardio-hepatic interactions have been recognized, their role in MI remains unknown. We treated cultured cardiomyocytes with conditioned media...

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Detalles Bibliográficos
Autores principales: Hakuno, Daihiko, Kimura, Masahiro, Ito, Shinji, Satoh, Junko, Nakashima, Yasuhiro, Horie, Takahiro, Kuwabara, Yasuhide, Nishiga, Masataka, Ide, Yuya, Baba, Osamu, Nishi, Hitoo, Nakao, Tetsushi, Nishino, Tomohiro, Nakazeki, Fumiko, Koyama, Satoshi, Hanada, Ritsuko, Randolph, Ruiz R., Endo, Jin, Kimura, Takeshi, Ono, Koh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233179/
https://www.ncbi.nlm.nih.gov/pubmed/30425314
http://dx.doi.org/10.1038/s41598-018-35194-w