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Herpes simplex virus type 2 infection triggers AP-1 transcription activity through TLR4 signaling in genital epithelial cells

BACKGROUND: The pattern recognition receptors (PPRs) are the earliest phase of the host defense against pathogens in genital epithelium, and toll-like receptors (TLRs) are best characterized PPRs mediating innate immune responses. Herpes simplex virus type 2 (HSV-2), a member of herpesviridae family...

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Detalles Bibliográficos
Autores principales: Lv, Xiaowen, Wang, Huanru, Su, Airong, Xu, Shijie, Chu, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233380/
https://www.ncbi.nlm.nih.gov/pubmed/30419930
http://dx.doi.org/10.1186/s12985-018-1087-3