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High content organelle trafficking enables disease state profiling as powerful tool for disease modelling

Neurodegenerative diseases pose a complex field with various neuronal subtypes and distinct differentially affected intra-neuronal compartments. Modelling of neurodegeneration requires faithful in vitro separation of axons and dendrites, their distal and proximal compartments as well as organelle tr...

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Detalles Bibliográficos
Autores principales: Pal, Arun, Glaß, Hannes, Naumann, Marcel, Kreiter, Nicole, Japtok, Julia, Sczech, Ronny, Hermann, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233479/
https://www.ncbi.nlm.nih.gov/pubmed/30422121
http://dx.doi.org/10.1038/sdata.2018.241