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High content organelle trafficking enables disease state profiling as powerful tool for disease modelling
Neurodegenerative diseases pose a complex field with various neuronal subtypes and distinct differentially affected intra-neuronal compartments. Modelling of neurodegeneration requires faithful in vitro separation of axons and dendrites, their distal and proximal compartments as well as organelle tr...
Autores principales: | Pal, Arun, Glaß, Hannes, Naumann, Marcel, Kreiter, Nicole, Japtok, Julia, Sczech, Ronny, Hermann, Andreas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233479/ https://www.ncbi.nlm.nih.gov/pubmed/30422121 http://dx.doi.org/10.1038/sdata.2018.241 |
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