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Triptolide as a novel agent in pancreatic cancer: the validation using patient derived pancreatic tumor cell line

BACKGROUND: Triptolide induces apoptosis and DNA damage followed by inhibition of DNA repair associated gene expression. However, there is the limited data for biomarker to predict the benefit to triptolide in various cancers including pancreatic cancer. METHODS: We investigated the anti tumor effic...

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Detalles Bibliográficos
Autores principales: Kim, Seung Tae, Kim, Sun Young, Lee, Jeeyun, Kim, Kyung, Park, Se Hoon, Park, Young Suk, Lim, Ho Yeong, Kang, Won Ki, Park, Joon Oh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233492/
https://www.ncbi.nlm.nih.gov/pubmed/30419860
http://dx.doi.org/10.1186/s12885-018-4995-0