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Downregulation of calcium-dependent NMDA receptor desensitization by sodium-calcium exchangers: a role of membrane cholesterol

BACKGROUND: The plasma membrane Na(+)/Ca(2+)-exchanger (NCX) has recently been shown to regulate Ca(2+)-dependent N-methyl-d-aspartate receptor (NMDAR) desensitization, suggesting a tight interaction of NCXs and NMDARs in lipid nanoclasters or “rafts”. To evaluate possible role of this interaction w...

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Detalles Bibliográficos
Autores principales: Sibarov, Dmitry A., Poguzhelskaya, Ekaterina E., Antonov, Sergei M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233507/
https://www.ncbi.nlm.nih.gov/pubmed/30419823
http://dx.doi.org/10.1186/s12868-018-0475-3