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PIAS1 protects against myocardial ischemia-reperfusion injury by stimulating PPARγ SUMOylation

BACKGROUND: Myocardial ischemia-reperfusion injury (IRI) has become one of the most serious complications after reperfusion therapy in patients with acute myocardial infarction. Small ubiquitin-like modification (SUMOylation) is a reversible process, including SUMO E1-, E2-, and E3-mediated SUMOylat...

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Detalles Bibliográficos
Autores principales: Xie, Bo, Liu, Xinyu, Yang, Jie, Cheng, Jinke, Gu, Jianmin, Xue, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233564/
https://www.ncbi.nlm.nih.gov/pubmed/30419807
http://dx.doi.org/10.1186/s12860-018-0176-x