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PIAS1 protects against myocardial ischemia-reperfusion injury by stimulating PPARγ SUMOylation
BACKGROUND: Myocardial ischemia-reperfusion injury (IRI) has become one of the most serious complications after reperfusion therapy in patients with acute myocardial infarction. Small ubiquitin-like modification (SUMOylation) is a reversible process, including SUMO E1-, E2-, and E3-mediated SUMOylat...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233564/ https://www.ncbi.nlm.nih.gov/pubmed/30419807 http://dx.doi.org/10.1186/s12860-018-0176-x |