H3K36 trimethylation mediated by SETD2 regulates the fate of bone marrow mesenchymal stem cells

During the aging process, bone marrow mesenchymal stem cells (BMSCs) exhibit declined osteogenesis accompanied by excess adipogenesis, which will lead to osteoporosis. Here, we report that the H3 lysine 36 trimethylation (H3K36me3), catalyzed by histone methyltransferase SET-domain-containing 2 (SET...

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Detalles Bibliográficos
Autores principales: Wang, Lijun, Niu, Ningning, Li, Li, Shao, Rui, Ouyang, Huiling, Zou, Weiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233919/
https://www.ncbi.nlm.nih.gov/pubmed/30422989
http://dx.doi.org/10.1371/journal.pbio.2006522

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233919/
https://www.ncbi.nlm.nih.gov/pubmed/30422989
http://dx.doi.org/10.1371/journal.pbio.2006522

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