Two herpesviral noncoding PAN RNAs are functionally homologous but do not associate with common chromatin loci

During lytic replication of Kaposi’s sarcoma-associated herpesvirus (KSHV), a nuclear viral long noncoding RNA known as PAN RNA becomes the most abundant polyadenylated transcript in the cell. Knockout or knockdown of KSHV PAN RNA results in loss of late lytic viral gene expression and, consequently...

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Detalles Bibliográficos
Autores principales: Withers, Johanna B., Li, Eric S., Vallery, Tenaya K., Yario, Therese A., Steitz, Joan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233925/
https://www.ncbi.nlm.nih.gov/pubmed/30383841
http://dx.doi.org/10.1371/journal.ppat.1007389

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233925/
https://www.ncbi.nlm.nih.gov/pubmed/30383841
http://dx.doi.org/10.1371/journal.ppat.1007389

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