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Two herpesviral noncoding PAN RNAs are functionally homologous but do not associate with common chromatin loci
During lytic replication of Kaposi’s sarcoma-associated herpesvirus (KSHV), a nuclear viral long noncoding RNA known as PAN RNA becomes the most abundant polyadenylated transcript in the cell. Knockout or knockdown of KSHV PAN RNA results in loss of late lytic viral gene expression and, consequently...
Autores principales: | Withers, Johanna B., Li, Eric S., Vallery, Tenaya K., Yario, Therese A., Steitz, Joan A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233925/ https://www.ncbi.nlm.nih.gov/pubmed/30383841 http://dx.doi.org/10.1371/journal.ppat.1007389 |
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