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Unraveling the transcriptional regulation of TWIST1 in limb development

The transcription factor TWIST1 plays a vital role in mesoderm development, particularly in limb and craniofacial formation. Accordingly, haploinsufficiency of TWIST1 can cause limb and craniofacial malformations as part of Saethre-Chotzen syndrome. However, the molecular basis of TWIST1 transcripti...

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Detalles Bibliográficos
Autores principales: Hirsch, Naama, Eshel, Reut, Bar Yaacov, Reut, Shahar, Tal, Shmulevich, Fania, Dahan, Idit, Levaot, Noam, Kaplan, Tommy, Lupiáñez, Darío G., Birnbaum, Ramon Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233932/
https://www.ncbi.nlm.nih.gov/pubmed/30372441
http://dx.doi.org/10.1371/journal.pgen.1007738