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A functional human motor unit platform engineered from human embryonic stem cells and immortalized skeletal myoblasts

BACKGROUND: Although considerable research on neuromuscular junctions (NMJs) has been conducted, the prospect of in vivo NMJ studies is limited and these studies are challenging to implement. Therefore, there is a clear unmet need to develop a feasible, robust, and physiologically relevant in vitro...

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Detalles Bibliográficos
Autores principales: Abd Al Samid, Marwah, McPhee, Jamie S, Saini, Jasdeep, McKay, Tristan R, Fitzpatrick, Lorna M, Mamchaoui, Kamel, Bigot, Anne, Mouly, Vincent, Butler-Browne, Gillian, Al-Shanti, Nasser
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233953/
https://www.ncbi.nlm.nih.gov/pubmed/30519053
http://dx.doi.org/10.2147/SCCAA.S178562