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A functional human motor unit platform engineered from human embryonic stem cells and immortalized skeletal myoblasts
BACKGROUND: Although considerable research on neuromuscular junctions (NMJs) has been conducted, the prospect of in vivo NMJ studies is limited and these studies are challenging to implement. Therefore, there is a clear unmet need to develop a feasible, robust, and physiologically relevant in vitro...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233953/ https://www.ncbi.nlm.nih.gov/pubmed/30519053 http://dx.doi.org/10.2147/SCCAA.S178562 |