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Efficient Production of On-Target Reads for Small RNA Sequencing of Single Cells Using Modified Adapters

[Image: see text] Although single-cell mRNA sequencing has been a powerful tool to explore cellular heterogeneity, the sequencing of small RNA at the single-cell level (sc-sRNA-seq) remains a challenge, as these have no consensus sequence, are relatively low abundant, and are difficult to amplify in...

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Detalles Bibliográficos
Autores principales: Khnouf, Ruba, Shore, Sabrina, Han, Crystal M., Henderson, Jordana M., Munro, Sarah A., McCaffrey, Anton P., Shintaku, Hirofumi, Santiago, Juan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233959/
https://www.ncbi.nlm.nih.gov/pubmed/30260208
http://dx.doi.org/10.1021/acs.analchem.8b02773