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Epitope resurfacing on dengue virus-like particle vaccine preparation to induce broad neutralizing antibody

Dengue fever is caused by four different serotypes of dengue virus (DENV) which is the leading cause of worldwide arboviral diseases in humans. Virus-like particles (VLPs) containing flavivirus prM/E proteins have been demonstrated to be a potential vaccine candidate; however, the structure of dengu...

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Detalles Bibliográficos
Autores principales: Shen, Wen-Fan, Galula, Jedhan Ucat, Liu, Jyung-Hurng, Liao, Mei-Ying, Huang, Cheng-Hao, Wang, Yu-Chun, Wu, Han-Chung, Liang, Jian-Jong, Lin, Yi-Ling, Whitney, Matthew T, Chang, Gwong-Jen J, Chen, Sheng-Ren, Wu, Shang-Rung, Chao, Day-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234032/
https://www.ncbi.nlm.nih.gov/pubmed/30334522
http://dx.doi.org/10.7554/eLife.38970