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Epitope resurfacing on dengue virus-like particle vaccine preparation to induce broad neutralizing antibody
Dengue fever is caused by four different serotypes of dengue virus (DENV) which is the leading cause of worldwide arboviral diseases in humans. Virus-like particles (VLPs) containing flavivirus prM/E proteins have been demonstrated to be a potential vaccine candidate; however, the structure of dengu...
Autores principales: | Shen, Wen-Fan, Galula, Jedhan Ucat, Liu, Jyung-Hurng, Liao, Mei-Ying, Huang, Cheng-Hao, Wang, Yu-Chun, Wu, Han-Chung, Liang, Jian-Jong, Lin, Yi-Ling, Whitney, Matthew T, Chang, Gwong-Jen J, Chen, Sheng-Ren, Wu, Shang-Rung, Chao, Day-Yu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234032/ https://www.ncbi.nlm.nih.gov/pubmed/30334522 http://dx.doi.org/10.7554/eLife.38970 |
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