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LPS‐stimulated NF‐κB p65 dynamic response marks the initiation of TNF expression and transition to IL‐10 expression in RAW 264.7 macrophages

During injury and infection, inflammation is a response by macrophages to effect healing and repair. The kinetics of the responses of proinflammatory TNF α, anti‐inflammatory IL‐10, and inflammatory master regulator NF‐κB elicited by lipopolysaccharide (LPS) may be critical determinants of the infla...

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Detalles Bibliográficos
Autores principales: Hobbs, Stuart, Reynoso, Marinaliz, Geddis, Alyssa V., Mitrophanov, Alexander Y., Matheny, Ronald W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234144/
https://www.ncbi.nlm.nih.gov/pubmed/30426723
http://dx.doi.org/10.14814/phy2.13914