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Ribosomal protein S27-like regulates autophagy via the β-TrCP-DEPTOR-mTORC1 axis
RPS27L (Ribosomal protein S27-like), an evolutionarily conserved ribosomal protein, is a p53 target and a physiological p53 regulator. We previously reported that Rps27l disruption enhanced lymphomagenesis in Trp53(+/)(−) mice by triggering genome instability and sensitized Trp53(+/)(−) mice to radi...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234217/ https://www.ncbi.nlm.nih.gov/pubmed/30425236 http://dx.doi.org/10.1038/s41419-018-1168-7 |